Shaanxi Yougu Biotechnology Co., Ltd
No.71#, Taibai South Rd, Zip 710065, Xi`an, China
Tel: +86-029-85390089
Mobile: +86-18740399038
Email: info@yougubio.com
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•Product name: Diosmin EP8.0
•Also known as: diosmetin 7-O-rutinoside, venosmine
•Molecular: C28H32O15
•CAS Number: 520-27-4
•Product code: YG-PA013
•Botanical source: Citrus limon (L.) Burm
•Certifications: ISO, HACCP, CQC, KOSHER, HALAL, GMP
•Specification: Diosmin EP8.0, Diosmin 90.0%~102.0%, Diosmin:Heperidin 90:10
Product Instruction
Diosmin Powder Instruction
◆ venosmine is a semi-synthetic flavonoid, a derivative of hesperidin. It is used to treat various vascular diseases including acne, varicose veins, poor leg circulation (venous stasis) and bleeding from the eye or gums (bleeding). It is also used to prevent liver toxicity. It is usually mixed with hesperidin.
◆ There are extensive clinical trials that show diosmin improves all stages of venous disease including venous ulcers and improves quality of life. pure diosmin is currently a prescription medication in some European countries, containing 90% venosmine and 10% hesperidin, and sold as a nutritional supplement in the United States.
Specification of Diosmin EP8.0
ITEMS | SPECIFICATIONS | METHOD/STANDARD | |
DESCRIPTION | |||
Characters | Powder | Organoleptic | |
Color | A grayish-yellow or light-yellow hygroscopic powder. |
Organoleptic | |
Odor | Characteristic | Organoleptic | |
Solubility
| Practically insoluble in water soluble in aqueous alkaline sol. |
In-House | |
Substances | Impurity A (Acetoisovanillone)≤1% | EP8.0 | |
Impurity B (Hesperidin) ≤5% | EP8.0 | ||
Impurity C (Isorhoifolin) ≤3% | EP8.0 | ||
Impurity E (Linarin) ≤3% | EP8.0 | ||
Impurity F (Diosmitin) ≤3% | EP8.0 | ||
Any other impurity≤1% | EP8.0 | ||
Total of other impurities and impurity A≤1% | EP8.0 | ||
Total impure≤10% | EP8.0 | ||
Water | ≤6.0% | EP8.0 | |
Sulphated ash | ≤0.2% | EP8.0 | |
Methanol | ≤3000ppm | EP8.0 | |
Pyridine | ≤200ppm | EP8.0 | |
Identification: | By HPLC/TLC | ||
Assay | 90.0%~102.0% | HPLC | |
Heavy Metals | ≤10ppm | EP8.0 | |
Pb | ≤1ppm | EP8.0 | |
As | ≤2ppm | EP8.0 | |
Hg | ≤0.1ppm | EP8.0 | |
Cd | ≤1.0ppm | EP8.0 | |
Microbiological | |||
Total Plate Count | 1000cfu/g Max | EP8.0 | |
Yeast&Mold | 100cfu/g Max | EP8.0 | |
E.Coli colonies/g | Negative (-) | EP8.0 | |
Samonella colonies/g | Negative (-) | EP8.0 |
Diosmin 90% Powder Benefits
◆ Resistant to inflammation and hyper susceptibility.
◆ Resistant to bacterium, include epiphyte and bacteria etc.
◆ Compared with other flavone plant, orange flavone has it own unique physiologic functions.
◆ Resistant to oxidation activity, includes to clear away single turn oxygen, peroxide, hydroxide radical and other free radical.
◆ Prevent circulatory system to be harmed by ill, make capillary vessel more flexible, resist platelet aggregation and regulate cardiovascular.
Application of Diosmin 90% Powder
◆ As a natural antioxidant, Diosmin Powder is mainly used in cosmetic industry.
◆ As a natural antioxidant, it is widely used in health product and food industry.
◆ As a raw material of drugs for lowering cholesterol, anti-virus and anti-inflammatory, it is mainly used in pharmaceutical field.
Citrus extract and derivatives series products
No. | Product Name | Specification |
1 | Diosmin | >90.0% |
2 | Hesperidin | >90.0% |
3 | Hesperidin Methyl Chalcone | >90.0% |
4 | Methyl Hesperidin | >94.0% |
5 | Hesperitin | >95.0% |
6 | Diosmetin | >98.0% |
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