Shaanxi Yougu Biotechnology Co., Ltd
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•Product name: L-Tetrahydropalmatine 98.0%
•Also known as: yan hu suo extract, Corydalis yanhusuo extract, Rotundine
•Product code: YG-PA007
•Botanical source: Corydalis yanhusuo
•L-Tetrahydropalmatine CAS No.: 483-14-7
•Formula: C21H25NO4
•Active Ingredient: L-Tetrahydropalmatine
•Certifications: ISO, HACCP, CQC, KOSHER, HALAL
•Specification: L-Tetrahydropalmatine 98.0%
Product Instruction
Product Instruction
◆Tetrahydropalmatine, also known as Yanhusuo B, is an analgesic alkaloid isolated from the traditional Chinese medicine Yanhusuo. There are two enantiomers of Corydalis yanhusuo extract , and the L-body has an antagonistic effect on dopamine The spirochete has no affinity for dopamine receptors, but can empty dopamine stored in nerve endings from neurons. It is a central nervous system inhibitor with analgesic, sedative, hypnotic and tranquilizing effects. Oral administration is easy to absorb, and the analgesic effect is fast.
◆Its analgesic effect is weaker than pethidine (durobutine), but it is stronger than general antipyretic analgesics. It has a good effect on chronic persistent dull pain, and has a poor trauma and post-operative pain. Large doses have a certain inhibitory effect on breathing. No obvious effect on liver function, no adverse effects on maternal and fetus. This product is not easy to produce drug resistance, and there is no addiction.
Specification of L-Tetrahydropalmatine 98.0%
ITEMS | SPECIFICATIONS | ANALYSIS |
Characters | Powder | Organoleptic |
Color | Light yellow to white crystal | Organoleptic |
Loss on drying | ≤5.0% | 3.86% |
Melting point | 141~144℃ | 142.7~143.4℃ |
Specific optical rotation Ignition Residue Absorbance Index Identification: | -290°~ -300° ≤0.1% 150~160 (wavelength 281nm) | -296.31° 0.03% 154.02 Positive |
IR
L-tetrahydropalmatine (Dry basis) | Sample spectrums are consistent with the reference standard spectrums. ≥98.5% |
Complies 99.07% |
Heavy Metals (Method: AAS) | ≤10ppm | CP2010 |
Pb | ≤1ppm | ICP-MS |
As | ≤1ppm | ICP-MS |
Hg | ≤0.1ppm | ICP-MS |
Cd | ≤0.2ppm | ICP-MS |
Microbiological | ||
Total Plate Count | 1000cfu/g Max | <100cfu/g |
Yeast&Mold | 50cfu/g Max | <10cfu/g |
E.Coli colonies/g | Negative | Negative |
Samonella colonies/g | Negative | Negative |
Product benefits
◆ Rotundinum has a protective effect on liver injury induced by carbon tetrachloride in mice.
◆ Corydalis yanhusuo extract has analgesia and sedative-hypnotic activity can depress the chthonic persistent pain and splanchna dull pain.
◆Rotundine has the effect of promoting blood circulation to remove blood stasis and promoting circulation of qi to relieve pain.
◆ L-tetrahydropalmatine is often used for hypochondriac pain due to stagnation of the liver-qi, stomachache due to stagnation of the stomach-qi, hernial pain.
Product application
◆ Rotundine has the effect of promoting blood circulation to remove blood stasis and promoting circulation of gas to relieve pain.
◆ Corydalis yan hu suo extract is often used for hypochondriac pain due to stagnation of the liver-gas, stomachache due to stagnation of the stomach-gas, hernial pain.
◆ Rotundinum has analgesia and sedative-hypnotic activity, can depress the chronic persistent pain and splanchnic dull pain. It has effect of promoting blood circulation to remove blood stasis and promoting circulation of qi to relieve pain.
◆ It is often used for hypochondriac pain due to stagnation of the liver-qi, stomachache due to stagnation of the stomach-qi, hernial pain. Tetrahydropalmatine has the protective effect on liver injury induced by carbon tetrachloride in mice.
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